106學年第1學期課程綱要

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一、課程基本資料
開課序號 2884 課程學制
科目代碼 BIU0148 課程名稱 免疫學
英文名稱 Immunology
全/半年 必/選修 選修
學分數 3.0 每週授課時數 正課時數: 3 小時
開課系級 生科系(學)4年級
先修課程 ◎必須先修過【BIU0044 遺傳學】、【BIU0143 生物化學】
課程簡介 This course will enable the student to gain a broad foundation base and build upon that base for understanding the defense mechanisms of the human body. These topics will include innate and adaptive immunity, antigen capture and recognition, mechanisms of immune reactions, immunological tolerance, immunological diseases, vaccine and immunological assays.
課程目標 對應系所核心能力
1. Demonstrate a comprehensive and practical understanding of basic immunological principles involved in research and clinical/applied science. 學士:
 1-1 具備生命科學之專業知識
2. Discuss current immunology news and issues 學士:
 1-1 具備生命科學之專業知識
 3-1 具備正確的科學態度,能主動探索生命科學之相關議題,並瞭解遵守科學倫理之重要性

二、教學大綱
授課教師 陳玫潔
教學進度與主題

Part I: An Introduction to Immunobiology and Innate Immunity
Chapter 1: Basic Concepts in Immunology
Chapter 2: Innate Immunity: The First Lines of Defense
Chapter 3: The Induced Responses of Innate Immunity

Part II: The Recognition of Antigen
Chapter 4: Antigen Recognition by B-cell and T-cell Receptors
Chapter 5: The Generation of Lymphocyte Antigen Receptors 
Chapter 6: Antigen Presentation to T Lymphocytes

Section Examination I (Ch1~5)

Part III: The Development of Mature Lymphocyte Receptor Repertoires
Chapter 7: Lymphocyte Receptor Signaling
Chapter 8: The Development and of B and T Lymphocytes

Part IV: The Adaptive Immune Response
Chapter 9: T Cell-Mediated Immunity 
Chapter 10: The Humoral Immune Response
Chapter 11: Integrated Dynamics of Innate and Adaptive Immunity 
Chapter 12: The Mucosal Immune System

Section Examination II (Ch6~11)

Part V: The Immune System in Health and Disease
Chapter 13: Failures of Host Defense Mechanisms
Chapter 14: Allergy and Allergic Diseases
Chapter 15: Autoimmunity and Transplantation
Chapter 16: Manipulation of the Immune Response

Paper Presentation and Discussion

Section Examination III  (Ch13~16)

教學方法
方式 說明
講述法  
討論法 課堂中針對相關時事進行討論
合作學習  
媒體融入教學 分組或個人完成報告
評量方法
方式 百分比 說明
期中考 40 % Section Examination I (Ch1~5), II (Ch6~11)
期末考 20 % Section Examination III  (Ch13~16)
課堂討論參與 10 %  
報告 20 % Paper Presentation and Discussion
其他 10 %  
參考書目

Janeway's Immunobiology, 9th edition, 2016. Written by Kenneth Murphy and Casey Weaver. Published by Garland Science. ISBN: 9780815345053

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