106學年第1學期課程綱要

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一、課程基本資料
開課序號 2552 課程學制
科目代碼 DIC8042 課程名稱 族群遺傳與演化甲
英文名稱 Population Genetics and Evolution A
全/半年 必/選修 必修
學分數 3.0 每週授課時數 正課時數: 3 小時
開課系級 生物多樣學位學程(博)碩博合開
先修課程
課程簡介 Population genetics is a discipline of genetics that studies the mechanism of gene frequency changes through time in a population and among populations. It is the fundamental basis of biological evolution. It also has been widely applied to the fields of medicine and agriculture. This course aims to introduce basic concepts of population genetics from causes of gene frequency changes to molecular evolution. Key topics in evolution will also be covered. This course should provide a solid base for other special topics in evolutionary biology and conservation, such as conservation genetics, molecular evolution, and evolutionary genomics.
課程目標 對應系所核心能力
1. Acquire the fundamental concepts of population genetics and evolution 博士:
 1-1 具備探究生命科學之專業知識
2. Learn how to critically read and evaluate scientific publications 博士:
 3-1 具備針對實驗結果,進行正確分析、歸納並發表研究成果的能力。
3. Identify interesting research questions and propose experimental tests in the 博士:
 3-1 具備針對實驗結果,進行正確分析、歸納並發表研究成果的能力。

二、教學大綱
授課教師 李壽先
教學進度與主題

Week 1 Class organization/Introduction/Thinking like a population geneticist

Week 2 Genotype frequencies

Week 3 Genetic drift and effective population size 1

Week 4 Genetic drift and effective population size 2

Week 5 Population structure and gene flow1

Week 6 Population structure and gene flow 2

Week 7 Mutation

Week 8 Natural selection 1

Week 9 Natural selection 2 (Midterm exam due)

Week 10 Molecular evolution 1

Week 11 Molecular evolution 2

Week 12 Clades/Trees

Week 13 Sexual selection

Week 14 Cooperation and conflict

Week 15 Speciation

Week 16 Evo-devo

Week 17 Co-evolution

Week 18 Final exam/”Grant reading committee”
教學方法
方式 說明
講述法 Lectures occur for some of the classes and is generally minimal.
討論法 Students must discuss reading material from text book and primary literature as well as homework problems
問題解決教學 Students must complete weekly problem sets
專題研究 Midterm is refereeing a paper; final is grant proposal
評量方法
方式 百分比 說明
作業 30 %  
期中考 15 %  
期末考 25 %  
課堂討論參與 30 %  
出席 30 %  
參考書目

Population Genetics, Matthew B. Hamilton (Wiley-Blackwell, 2009)

Evolution 2nd Edition, Douglas J. Futuyma (Sinauer Associates, Inc, 2009)

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